Working in an office full-time for many years was really hard on my body. I was constantly at the chiropractor with a sore neck and body. New evidence suggests there are more serious issues with sitting at a desk for long periods of time –

Prolonged sitting puts unhealthy forces on your body that can ultimately lead to serious ailments. When you sit for a long period of time, your metabolism level decreases. Sitting down for most of the day, like many of us do at work, has been linked to an increased risk of chronic diseases, such as heart disease, and type-2 diabetes. Sitting time, such as that spent watching television and driving the car, contributes to an increase in premature mortality risk.

A daily 30-minute exercise routine may not be enough, since the remainder of the day is spent idle. A recent study showed that those who took more breaks from sitting throughout the day had slimmer waists, lower body mass indexes and healthier blood fat and blood sugar levels than those who sat the most. This was regardless of the intensity of the work out.

Here is a link to a web application that reminds you to take breaks, move around and stretch:

https://addons.mozilla.org/en-us/firefox/addon/stretchclock/